Changes in transmitter release induced by ion-containing liposomes.
نویسندگان
چکیده
The changes in quantal transmitter release induced by egg phosphatidylcholine liposomes with different internal ionic composition were examined at the frog neuromuscular junction by using conventional electrophysiological techniques. It was found that liposomes containing calcium or sodium ions increase both evoked and spontaneous transmitter release, while liposomes containing potassium do not. The results suggest that phosphatidylcholine liposomes are able to transfer their aqueous medium into the presynaptic nerve terminal.
منابع مشابه
Primary and secondary regulation of quantal transmitter release: calcium and sodium.
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عنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 75 10 شماره
صفحات -
تاریخ انتشار 1978